Streptococcus pneumoniae -associated hemolytic uremic syndrome in Thai children

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Hemolytic uremic syndrome associated with Streptococcus pneumoniae.

he hemolytic uremic syndrome (HUS) is characterized by the simultaneous occurrence of the triad of acute renal insufficiency, microangiopathic hemolytic anemia and thrombocytopenia. The HUS is the most common cause of acute renal failure in infants and young children in western countries. It could be classified into diarrhea positive, D+ (typical) or diarrhea negative, D(atypical) HUS. In Europ...

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Streptococcus pneumoniae infection and hemolytic uremic syndrome.

Sr. Director: Recently it has published in Nefrologia a case of haemolytic uremic syndrome associated to pneumococcal infection (SP-HUS) in a 2-year-6-month old boy with pneumonia, that required veno-venous hemodiafiltration / hemofiltration during ten days. SP-HUS is an uncommon disease whose incidence, following invasive pneumococcal infection, is estimated at 0.4-0.6 %. Its mortality rate is...

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Streptococcus pneumoniae-associated hemolytic uremic syndrome among children in North America.

BACKGROUND To better characterize Streptococcus pneumoniae-associated hemolytic-uremic syndrome (SP-HUS), we report the largest series of SP-HUS among children in North America. METHODS We surveyed pediatric members of the Emerging Infections Network to identify SP-HUS cases. Respondents contributed clinical and laboratory features of these pediatric cases. RESULTS A total of 37 cases occur...

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Hemolytic uremic syndrome in children: Seizure disorders and mortality rate

Background and Objective: Hemolytic Uremic Syndrome (HUS) is a thrombotic microangiopathy that contains hemolytic anemia, thrombocytopenia, renal failure and other organ involvement including central nervous system. Frequency of neurologic complications in patients with HUS is high and important cause of mortality. This study was performed to determine seizure disorders in term of acute neurolo...

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Conjugated Hyperbilirubinemia in a Child with Streptococcus pneumoniae-associated Hemolytic Uremic Syndrome

Conjugated hyperbilirubinemia is a rare complication of hemolytic uremic syndrome (HUS). We report a case of a 2-year-old female with Streptococcus pneumonia-associated HUS (SP+ HUS) who developed severe cholestasis. It is important for pediatric gastroenterologists to be aware of manifestations of HUS, and that although rare, cholestasis can be one of the early findings in patients with SP+ HUS.

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2012

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2012.05.791